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Furthermore, GEN are reported to induce liver cancer MHCC97-L cells apoptosis and activity of caspase-3 and caspase-9 through inhibiting JNK pathway (Liu et al., 2019)

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The underlying mechanism involves the suppression of NF-B and STAT3 signaling pathways, which are crucial in the inflammatory response associated with PsO

P -values derived from a Wilcoxon rank-sum test, followed by adjustment by the BenjaminiHochberg procedure to correct for multiple testing

Discussion As the most abundant amino acid in circulation, Gln exerts an antioxidant defense function against oxidative stress by supporting GSH synthesis [21,22,23]